Yes. As long as your camera model is supported by your version of Adobe Lightroom or Photoshop ACR.
It is quite different. The All Films 5 is not a replacement for All Films 4, it's just a new tool based on the new underlaying principles and featuring a range of updated and refined film looks. Among its distinctive features are:
– New film looks (best film stocks, new flavours)
– Fully profile-based design, means more room for your own edits
– Film-like highlight compression
– Native look strength adjustment